MOG 46 - 54

MOG 46 - 54
€50.00 *

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Delivery time 3 weeks
sterile and endotoxin free Delivery Format:
The product is supplied freeze dried as trifluoracetate salt

Amount in mg:

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  • EP09874_1
Myelin oligodendrocyte glycoprotein (MOG) 46 - 54, a minor component of CNS myelin, is expressed... more
Product information "MOG 46 - 54"
Myelin oligodendrocyte glycoprotein (MOG) 46 - 54, a minor component of CNS myelin, is expressed in central nervous system myelin which produces a relapsing-remitting neurological diesease with extensive plague-like demyelination. It is believed to be a target autoantigen in multiple sclerosis. MOG 46 - 54 peptide is an immunodominant epitope of MOG that induces strong T and B cell responses and Induces experimental autoimmune encephalomyelitis in rodents. A single injection of this peptide produces a relapsing-remitting neurologic disease with extensive plaque-like demyelination. This Cysteine containing MOG 46 - 54 peptide can be use to induced polyclonal anti-MOG 46 - 54 antibody production in rabbits with high specificity, high affinity, and high titer indicating its high purity, as well as suitability for peptide-coated ELISA and Western blot assay. Immunization with MOG 46 - 54 suppresses spontaneous regeneration of dopaminergic neurons injured with MPTP. Multiple Sclerosis: MOG 46 - 54 induced experimental autoimmune encephalomyelitis (EAE) rodent models

 
Sequence:RVVHLYRNG
Gene:mog
Delivery: 3 weeks
C-Terminus:OH
N-Terminus:H
Purity:95%
Amount:1 mg
Counter Ion:TFA
Protein:Myelin oligodendrocyte glycoprotein
Species:Mouse, Rat
Application :Multiple Sclerosis
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