WT1 37-45 (HLA-A*02:01)

€57.50 *

Delivery time 2-3 days
sterile and endotoxin free
Delivery Format: The product is supplied freeze dried.

Order number: EP11469_1

Wilms tumor protein is a protein that is encoded by the WT1 gene on chromosome 11p in humans.... more

Product information "WT1 37-45 (HLA-A*02:01)"

Wilms tumor protein is a protein that is encoded by the WT1 gene on chromosome 11p in humans. WT1 is a tumour suppressor gene associated with the development of Wilms' Tumour, from which it was named. Mutations in exon 7 and 9 of WT1 have been recurrently identified in acute myeloid leukemia and associated with poorer prognosis and chemotherapy resistance. The WT1 peptide is a transcription factor that contains four zinc finger motifs at the C-terminus and a proline / glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system. WT1 has been ranked by the National Cancer Institute (NCI) as the Number 1 target for cancer immunotherapy.

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Sequence:	VLDFAPPGA
Gene:	WT1
Delivery:	2-3 days
C-Terminus:	OH
N-Terminus:	H
Purity:	95%
Amount:	1 mg
Counter Ion:	TFA
Protein:	Wilms-Tumor-Protein
Species:	Human
Allele:	HLA-A*02:01
Indication :	Cancer