Trp2 180-188

This peptide is derived from tyrosinase-related protein 2 (TRP-2) residues 180-188. TRP-2 peptide, also named L-dopachrome tautomerase, H-2KB or DCT, belongs to the melanocyte differentiation antigens and has been implicated as a target for immunotherapy of human as well as murine melanoma. Studies show that this TRP2 derived peptide can bind to mouse and human MHC class molecules. Immunization with TRP-2 peptide loaded dendritic cells (DCs) results in effective induction of antitumor immunity.
Antigen Peptide L-dopachrome tautomerase H-2 Kb (SVYDFFVWL) for stimulation of antigen-specific T cells in T cell assays such as ELISPOT, ICS, cytotoxity or proliferation assays.

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