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Structure of HCMV UL40 15-23 (HLA-E)
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Infectious disease

HCMV UL40 15-23 (HLA-E) VMAPRTLIL

Product number: EP06244_1

€ 105.00 *

Prices excl. VAT plus shipping costs
Available, delivery time: 1-3 days
sterile and endotoxin free
Delivery Format: The product is supplied freeze dried.
Purity: 95% HPLC-MS
Caution: For research use only. Not for use in humans.
Amount in mg
1
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Description

VMAPRTLIL is a linear peptidic epitope (epitope ID69921) studied as part of HLA class I histocompatibility antigen, Cw-14 alpha chain from Homo sapiens (human), HLA class I histocompatibility antigen, Cw-5 alpha chain from Homo sapiens (human), HLA class I histocompatibility antigen, Cw-2 alpha chain from Homo sapiens (human), HLA class I histocompatibility antigen, Cw-4 alpha chain from Homo sapiens (human), HLA class I histocompatibility antigen, Cw-3 alpha chain from Homo sapiens (human), Protein UL40 from Human herpesvirus 5 (Human cytomegalovirus), HLA class I histocompatibility antigen, Cw-8 alpha chain from Homo sapiens (human), HLA class I histocompatibility antigen, Cw-12 alpha chain from Homo sapiens (human), HLA class I histocompatibility antigen, Cw-16 alpha chain from Homo sapiens (human), HLA class I histocompatibility antigen, Cw-17 alpha chain from Homo sapiens (human) and Unidentified protein from Unidentified. This epitope has been studied for immune reactivity, tested in T cell assays and MHC ligand assays

TechData

Sequence: VMAPRTLIL
Gene: UL111A
Delivery: 1-3 days
C-Terminus: OH
N-Terminus: H
Amount: 1 mg
Counterion: TFA
Protein: Viral interleukin-10 homolog
IEDB Id: https://www.iedb.org/epitope/69921
Species: Human cytomegalovirus (Human herpesvirus 5)
Allele: HLA-E*
Application: Flow Cytometry
Indication: Infectious disease, Cancer, Neuroscience, Diabetes
Purity: 95% HPLC-MS

Documents

Material data sheet Safety data sheet Storage and handling of peptides Probing of membranes with HRP

References

Vietzen, Hannes et al. “Torque teno viruses exhaust and imprint the human immune system via the HLA-E/NKG2A axis.” Frontiers in immunology vol. 15 1447980. 4 Sep. 2024, doi:10.3389/fimmu.2024.1447980

Martín Almazán, Nerea et al. “Non-classical HLA-E restricted CMV 15-mer peptides are recognized by adaptive NK cells and induce memory responses.” Frontiers in immunology vol. 14 1230718. 21 Sep. 2023, doi:10.3389/fimmu.2023.1230718
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