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Beta-Amyloid Peptides – the Secret Stars behind Lecanemab
The fact that Alzheimer's patients can now benefit from Lecanemab is thanks not only to the hard-working scientists in this research area but also to the beta-amyloid peptides. Here’s how peptides were instrumental in the development process:
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Reflecting on an inspiring SITC2024
We had a great time at this year‘s 39th Annual Meeting of the Society for Immunotherapy of Cancer (SITC 2024) in Houston, Texas, sharing our latest advancements in peptide synthesis with the cancer immunotherapy community:
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Esophagogastric adenocarcinoma: Tumor-associated antigens, immune responses and HLA-I expression
Researchers have identified the most significant tumor-associated antigens in esophagogastric adenocarcinoma and determined how endogenous T cells and antibodies reacted to them. They also investigated the influence of HLA homozygosity.
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Quality control of peptide pools in personalized cancer therapy
The quality of peptide pools is crucial for the accuracy of immunotherapies, but the quality control of these complex products is a challenge. Researchers at the BAM in Berlin evaluated the effectiveness of UHPLC coupled with two different detectors.
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Neoantigene-Specific T-Cells in TIL Therapy
The newly approved Lifileucel stimulates tumor-infiltrating lymphocytes (TILs) unspecifically. Researchers are now investigating the degree to which neoantigens contribute to tumor regression under TIL therapy.
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Peptide Pools: Powerful Tools in Immune Research
Peptide pools cover long peptide sequences and even entire proteins. They can stimulate antigen-specific CD4+ and CD8+ T cells efficiently and cost-effectively.
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IMMUNOLOGY 2024™: a buzzing booth, high-profile journals and three plush elephants
From May 4th to 6th, peptides&elephants participated in the IMMUNOLOGY2024 conference at the AAI Meeting in Chicago, Illinois – the leading annual immunology event worldwide.
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Tumor Immunology meets Oncology: Insights from the TIMO XVIII Symposium
The recent Symposium Tumor Immunology meets Oncology XVIII (TIMO XVIII) at the Old Townhall in Brandenburg at the Havel, Germany, served once again as a nexus for leading scientists, clinicians and young researchers from 13 different countries.
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Adoptive T cell therapy: Highly effective PRAME-specific T cell receptor identified
Researchers led by Nadja Sailer from Medigene Immunotherapies GmbH have taken an important step forward in the treatment of melanoma and other solid tumors: They found a highly effective PRAME-specific T cell receptor for adoptive T cell therapy.
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Endotoxin contamination triggers severe symptoms
Endotoxin originates from the outer membrane of gram-negative bacteria. When endotoxin is present in vaccines and other injectable drugs, pyrogenic reactions can occur, ranging from fever and chills to fatal septic shock.
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Students meet peptides - to learn more about peptide synthesis
Students meet peptides - to learn more about peptide synthesis as part of the career orientation project week
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FACS analysis showed: CMV-specific T cells respond to leukemia antigen
November 18, 2023
Dr. Lilian Schoefer
Research updates FACS analysis, myeloid leukemia, cytomegalovirus, CMV
Research updates FACS analysis, myeloid leukemia, cytomegalovirus, CMV
Using FACS analysis and peptide pools from peptides&elephants, they tested whether reactivation of the cytomegalovirus influences T cell immunity against Wilms tumor 1 - and thus against leukemia cells.
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Epstein-Barr virus: Mechanisms of cancer development decoded - Pioneering research with peptides from peptides&elephants
Over 90 percent of adults worldwide are infected with the Epstein-Barr virus (EBV). The virus belongs to the herpes viruses and stays in the body for a lifetime.
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P&E’s participation and sponsorship of AAI conference - IMMUNOLOGY 2023™ workshop on peptide pools in Washington DC in May 2023
P&E sponsored and participated in the AAI conference 2023 in Washington, USA. CEO Dr. Oliver Kreuzer held a workshop on peptide pools, elucidating their design, manufacturing and applications.
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Exponential increase in the BA.5 Omicron Subtype
Omicron is currently accounting for over 99% of all SARS-CoV-2 infections in Germany. Since calendar week 14, an exponential increase in the BA.5 Omicron Subtype is reported. We synthesized the BA.5 Omicron Peptide Pool immediately.
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Personalized Cancer Vaccines
peptides & elephants received 1 Million USD funding for the development of the high parallel Ultrasound Peptide Synthesis, USPS®.
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