Structure of HPV16/18 E6 31-38 (HLA-B*40:02)

Infectious disease

HPV16/18 E6 31-38 (HLA-B*40:02) HDIILECV

Product number: EP14315_1

€ 105.00 *

Prices excl. VAT plus shipping costs

Available, delivery time: 3 weeks

sterile and endotoxin free

Delivery Format: The product is supplied freeze dried.

Purity: 95% HPLC-MS

Caution: For research use only. Not for use in humans.

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Description

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Description

HDIILECV is a linear peptidic epitope studied as part of Protein E6 from Alphapapillomavirus 9, tested in T cell assays.

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Sequence:	HDIILECV
Gene:	E6
Delivery:	3 weeks
C-Terminus:	OH
N-Terminus:	H
Amount:	1 mg
Counterion:	TFA
Protein:	Protein E6
UniProt Id:	P03126
Species:	HPV 16, HPV 18
Allele:	HLA-B*40:02
Application:	Flow Cytometry
Indication:	Infectious disease, Cancer
Purity:	95% HPLC-MS

Documents

Storage and handling of peptides

Probing of membranes with HRP

More HPV E6 Peptides

HPV16 E6 29-38 (HLA-A*02:01)

TIHDIILECV is a linear peptidic epitope (epitope ID64320) studied as part of Protein E6 from Human papillomavirus type 16 (UniProt: P03126). This epitope has been studied for immune reactivity, tested in T cell assays, B cell assays and MHC ligand assays.

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HPV16 E6 48-57 (H-2Kb)

EVYDFAFRDL is a linear peptidic epitope (epitope ID 14909) studied as part of Protein E6 (UniProt:P03126) from Human papillomavirus type 16 (HPV-16). HPV-16, along with HPV-31, HPV-33, HPV-35, HPV-52, HPV-58 and HPV-67, belongs to Alphapapillomavirus 9.E6 plays a key role in triggering and maintaining the transformation of normal host cells into cancerous ones. It primarily acts as an oncoprotein by promoting the breakdown of several key regulatory proteins in the host cell.

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HPV16 E6 52-61 (HLA-B*35:01)

FAFRDLCIVY is a linear peptidic epitope (epitope ID 110575) studied as part of Protein E6 (UniProt:P03126) from Humanes Papillomvirus 16 (HPV-16). This epitope has been studied for immune reactivity and has been tested in T cell assays and an MHC ligand assay. The high-risk HPV-16 is known for its association with cervical cancers and other anogenital cancers. HPV-16 is part of the Alphapapillomavirus 9 group, which also includes HPV-31, HPV-33, HPV-35, HPV-52, HPV-58 and HPV-67.

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HPV16 E6 64-72 (HLA-A*03:01)

KLCLRFLSK is a linear peptidic epitope (epitope ID 1330496) derived from the E6 protein of Human papillomavirus type 16 (HPV-16), as annotated under UniProt entry P03126. This epitope has been explored in the context of E6s role in viral pathogenesis. HPV-16 is a member of the Alphapapillomavirus 9 species group, which also includes HPV-31, -33, -35, -52, -58, and -67. The E6 protein contributes significantly to the development and persistence of cellular transformation, a process where normal cells are altered into malignant ones. It functions predominantly as an oncoprotein, accelerating the degradation of multiple host regulatory proteins that normally control cell growth and survival.

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HPV16 E6 86-94 (HLA-A*11:01)

NTLEQTVKK is a linear peptidic epitope (epitope ID 922935) studied as part of Protein E6 (UniProt:P03126) from Human papillomavirus type 16. HPV 16 E6 86-94 has been studied for immune reactivity and has been tested in T cell assays.HPV-16 belongs to Alphapapillomavirus 9, together with HPV-31, HPV-33, HPV-35, HPV-52, HPV-58 and HPV-67.

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HPV16/18 E6 133-142 (HLA-A*68:01)

HNIRGRWTGR is a linear peptide epitope (ID: 110285) originating from the E6 oncoproteins of Human papillomavirus type 16 (UniProt: P03126) and type 18 (UniProt: P06463). It corresponds to amino acids 133 to 142 of the E6 protein sequence and has been investigated for its immunogenic properties, including its recognition by T cells in functional immune assays. HPV-16 and HPV-18 belong to different species groups within the Alphapapillomavirus genus HPV-16 is part of Alphapapillomavirus 9, while HPV-18 belongs to Alphapapillomavirus 7. Both are considered high-risk oncogenic types, with HPV-16 being the most prevalent and HPV-18 the second most common type found in cervical cancers. The E6 protein is crucial to the viruss ability to interfere with host cell regulation. It contributes to cancer development by targeting and degrading tumor suppressor proteins, thereby undermining normal cell cycle control and promoting uncontrolled cell proliferation. The E6 region containing this epitope is particularly relevant for immune-based studies due to its potential to elicit virus-specific T cell responses.

Ab 105,00 €*

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HPV16/18 E6 75-83 (HLA-A*24:02)

EYRHYCYSL is a linear peptidic epitope (epitope ID 110846) studied as part of Protein E6 (UniProt:P03126) from Human papillomavirus type 16 and Protein E6 (UniProt:P06463) from Human papillomavirus type 18. This epitope has been studied for immune reactivity and has been tested in T cell assays, a B cell assay and MHC ligand assays.

Ab 105,00 €*

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HPV16/18 E6 87-95 (HLA-A*24:02)

CYSLYGTTL is a linear peptidic epitope (epitope ID 7439) studied as part of Protein E6 (UniProt:P03126) from Human papillomavirus type 16 and Protein E6 (UniProt:P06463) from Human papillomavirus type 18. This epitope has been studied for immune reactivity, tested in T cell assays and MHC ligand assays.Human papillomavirus type 16 belongs to Alphapapillomavirus 9 and Human papillomavirus type 18 to Alphapapillomavirus 7.

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HPV Peptide Pools

Tipp

HPV Sub Peptide Pool (>95% HPLC)

This pool consists of 14 peptides, each corresponding to a defined HLA class I-restricted T cell epitope from human papilloma virus (HPV).

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HPV16 (L1) Peptide Pool

Pool of 124 peptides derived from a peptide scan (15mers with 11 aa overlap) through Protein L1 (Swiss-Prot ID: Q9WLQ6) of Human papillomavirus - type 16 One unit allows the stimulation of 2,5 x 108 cells.

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HPV16 (L2) Peptide Pool

Pool of 116 peptides derived from a peptide scan (15mers with 11 aa overlap) through Protein L2 (Swiss-Prot ID: P03107) of Human papillomavirus - type 16. One unit allows the stimulation of 2,5 x 108 cells.

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HPV16 E2 Peptide Pool

Pool of 89 peptides derived from a peptide scan (15mers with 11 aa overlap) through Regulatory protein E2 (UniProt ID: P03120) of Human papillomavirus type 16. One unit allows the stimulation of 2,5 x 108 cells.

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HPV16 E5 Peptide Pool

Pool of 18 peptides derived from a peptide scan (15mers with 11 aa overlap) through Probable protein E5 (UniProt ID: P06927) of Human papillomavirus type 16. One unit allows the stimulation of 2,5 x 108 cells.

261,90 €*

HPV16 E6 Peptide Pool

Pool of 37 peptides derived from a peptide scan (15mers with 11 aa overlap) through Protein E6 (Swiss-Prot ID: P03126) of Human papillomavirus type 16. One unit allows the stimulation of 2,5 x 108 cells.

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HPV16 E7 Peptide Pool

Pool of 22 peptides derived from a peptide scan (15mers with 11 aa overlap) through Protein E7 (Swiss-Prot ID: P03129) of Human papillomavirus. One unit allows the stimulation of 2,5 x 108 cells.

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HPV18 (L1) Peptide Pool

Pool of 140 peptides derived from a peptide scan (15mers with 11 aa overlap) through Protein L1 (Swiss-Prot ID: P06794) of Human papillomavirus - type 18. One unit allows the stimulation of 2,5 x 108 cells.

321,00 €*

HPV18 (L2) Peptide Pool

Pool of 113 peptides derived from a peptide scan (15mers with 11 aa overlap) through Protein L2 (Swiss-Prot ID: P06793) of Human papillomavirus. One unit allows the stimulation of 2,5 x 108cells.

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HPV18 E2 Peptide Pool

Pool of 89 peptides derived from a peptide scan (15mers with 11 aa overlap) through Regulatory protein E2 (UniProt ID: P06790) of Human papillomavirus type 18. One unit allows the stimulation of 2,5 x 108 cells.

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HPV18 E5 Peptide Pool

Pool of 16 peptides derived from a peptide scan (15mers with 11 aa overlap) through Probable protein E5 (UniProt ID: P06792) of Human papillomavirus type 18. One unit allows the stimulation of 2,5 x 108 cells.

261,90 €*

HPV18 E6 Peptide Pool

Pool of 37 peptides derived from a peptide scan (15mers with 11 aa overlap) through Protein E6 (UniProt ID: P06463) of Human papillomavirus type 18. One unit allows the stimulation of 2,5 x 108 cells.

261,90 €*

HPV18 E7 Peptide Pool

Pool of 24 peptides derived from a peptide scan (15mers with 11 aa overlap) throughProtein E7(UniProt ID: P06788) of Human papillomavirus type 18. One unit allows the stimulation of 2,5 x 108cells.

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HPV16/18 E6 31-38 (HLA-B*40:02) HDIILECV

€ 105.00 *

Description

TechData

Documents