BCR-ABL 926-934 (HLA-A*02:01) SSKALQRPV
€105.00*
Description
In chronic myelogenous leukemia, a translocation occurs between chromosomes 9 and 22, which leads to a BCR-ABL fusion gene. This results in chimeric proteins.
The nonapeptide BCR-ABL 926-934 (epitope ID 2187155) with the amino acid sequence SSKALQRPV from the junctional region of the BCR-ABLb3a2 molecule has been shown to be immunogenic. It could therefore be useful for developing a specific immunotherapy for patients with chronic myelogenous leukemia.
BCR-ABL 926-934 binds to HLA-A2.1 molecules and triggers primary reactions of cytotoxic T lymphocytes in vitro.
TechData
| Sequence: | SSKALQRPV |
| Gene: | BCR |
| Delivery: | 3 weeks |
| C-Terminus: | OH |
| N-Terminus: | H |
| Amount: | 1 mg |
| Counterion: | TFA |
| Protein: | Human Bcr-abl 210 kD fusion protein |
| Species: | Human |
| Allele: | HLA-A*02:01 |
| Application: | Flow Cytometry |
| Indication: | Cancer |
| Purity: | 95% HPLC-MS |
Documents
References
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