Peptide Insights – Immunology & Virus Research with peptides&elephants

Discover how peptides illuminate pathogen and tumor biology – from EBV-driven lymphomas and TIL-based melanoma therapies to PRAME-targeted strategies and Influenza A Matrix Protein 1.

Graphic showing a man with highlighted immunological features and a molecular model of the LMP-1 peptide next to a virus particle.

EBV-Lymphoma Study: Modeling NK Cell Evasion

A synthetic LMP-1 peptide (GGDPHLPTL) revealed mechanisms of HLA-E-mediated NK cell evasion in EBV-related lymphoma.

-> The study in a nutshell

Illustration of cells and a person sitting in a lab holding a test tube next to a microscope

TIL Therapy in Melanoma: Peptide Tools for MAAs

An introduction to TILs in melanoma, their MAA and neoantigen targets, and strategies to enrich potent populations for therapy...

-> Explore TIL insights

Chemical structure formula with highlighted group and text boxes reading 'PRAME 425-433', 'Biomarker', 'Retinoic acid signalling', 'Melanoma', and 'Therapeutic target' next to a person in a lab coat holding a clipboard.

PRAME Cancer-Testis Antigen: Peptide Target for Immunotherapy

PRAME, overexpressed in various malignancies, serves as an immunotherapeutic target. Dive into its function in tumorigenesis, its diagnostic value, and translational applications.

-> Read PRAME insights

Schematic diagram of an influenza A virus labeled with hemagglutinin, neuraminidase, matrix protein 1, M2, vRNP, NS1, NS2/NEP, and components nucleoprotein, lipid bilayer, and RNA polymerase

Matrix Protein 1 of Influenza A: Peptide Epitopes & Function

Matrix Protein 1 (M1) drives viral stability, uncoating, assembly, and budding. Learn about its domains, peptide epitopes, and role in the viral life cycle.

-> View M1 insights