Cancer
Survivin Peptide Pool, human
€237.50*
Prices excl. VAT plus shipping
costs
Available, delivery time:
1-3 days
sterile and endotoxin free
Delivery Format: The product is supplied freeze dried.
Caution:
For research use only. Not for use in humans.
1
Product number: LB01349
Description
Peptide pool of 33 overlapping peptides derived from a peptide scan (15mers with 11 aa overlap) through Baculoviral IAP repeat-containing protein 5 (UniProt ID O15392) for T cell assays.
One unit allows the stimulation of 2,5 x 108 cells.
You can find applications and references in our blog:
FACS analysis showed: CMV-specific T cells respond to leukemia antigen >
Esophagogastric adenocarcinoma: Tumor-associated antigens, immune responses and HLA-I Expression >
TechData
| Gene: | BIRC5 |
| Delivery: | 1-3 days |
| Counterion: | TFA |
| Length: | 142 amino acids |
| No. Peptides: | 33 peptides |
| Amount/Aliquote: | 15 nmol (approx. 25µg)/peptide for stimulation of 2,5 x 108 cells |
| Solubility: | Dissolve in a minimum amount of pure DMSO (40µl) and dilute with water to the desired concentration. Please pay attention that the final concentration of DMSO must be below 1% (v/v) to avoid toxicity in the biological system. |
| Protein: | Baculoviral IAP repeat-containing protein 5 |
| UniProt Id: | O15392 |
| Species: | Human |
| Application: | T-cell assays, Immune monitoring, Antigen specific T-cell stimulation, T-cell expansion, Cellular immune response |
| Indication: | Cancer |
Documents
References
Thelen M, Keller D, Lehmann J, et al.: Immune responses against shared antigens are common in esophago-gastric cancer and can be enhanced using CD40-activated B cells. Journal for ImmunoTherapy of Cancer 2022;10:e005200. doi: 10.1136/jitc-2022-005200
Luo, Xiao-Hua et al.: Different recovery patterns of CMV-specific and WT1-specific T cells in patients with acute myeloid leukemia undergoing allogeneic hematopoietic cell transplantation: Impact of CMV infection and leukemia relapse. Frontiers in immunology vol. 13 1027593. 7 Feb. 2023, doi:10.3389/fimmu.2022.1027593
Luo, Xiao-Hua et al.: Different recovery patterns of CMV-specific and WT1-specific T cells in patients with acute myeloid leukemia undergoing allogeneic hematopoietic cell transplantation: Impact of CMV infection and leukemia relapse. Frontiers in immunology vol. 13 1027593. 7 Feb. 2023, doi:10.3389/fimmu.2022.1027593