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Structure of Influenza A HA 271-286 Peptide

Infectious disease

Influenza A HA 271-286 Peptide RGYFKMRTGKSSIMRS

Product number: EP21291_1M

€133.20*

Prices excl. VAT plus shipping costs

Available, delivery time: 3-4 weeks

sterile and endotoxin free

Delivery Format: The product is supplied freeze dried.

Purity: 95% HPLC-MS

Caution: For research use only. Not for use in humans.

Amount in mg

1

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Description

The Influenza A HA 271–286 Peptide (RGYFKMRTGKSSIMRS, IEDB Epitope ID: 54022) is a highly promiscuous, 16-mer CD4+ T-cell epitope derived from Influenza A Hemagglutinin (UniProt ID: P03437). Characterized by its broad MHC Class II binding spectrum, this linear peptide binds with high affinity to HLA-DQA1*01:02 / DQB1*06:02 as well as HLA-DRB1*10:01 and HLA-DRB1*01:01.

Due to its ability to be presented across multiple common HLA class II alleles, this sequence is a key target for studying helper T-cell priming, cross-reactive CD4+ responses, and population-wide immunomonitoring. Depending on whether the numbering scheme includes the precursor signal peptide (HA0) or refers to the processed chain, this sequence is annotated as HA 271–286 or HA 255–270.

TechData

Sequence:	RGYFKMRTGKSSIMRS
Gene:	HA
Delivery:	3-4 weeks
C-Terminus:	OH
N-Terminus:	H
Amount:	1 mg
Counterion:	TFA
Protein:	Hemagglutinin
UniProt Id:	P03437
IEDB Id:	54022
Species:	Influenza A virus
Allele:	HLA-DRB101:01, HLA-DRB110:01, HLA-DQA101:02/DQB106:02
Application:	Antigen specific T-cell stimulation, T-cell assays, T-cell expansion
Indication:	Infectious disease
Purity:	95% HPLC-MS

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Storage and handling of peptides

Probing of membranes with HRP

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