MOG 8 - 22, rat
Myelin oligodendrocyte glycoprotein (MOG) 8 - 22, a minor component of CNS myelin, is expressed in central nervous system myelin which produces a relapsing-remitting neurological diesease with extensive plague-like demyelination. It is believed to be a target autoantigen in multiple sclerosis. MOG 8 - 22 peptide is an immunodominant epitope of MOG that induces strong T and B cell responses and Induces experimental autoimmune encephalomyelitis in rodents. A single injection of this peptide produces a relapsing-remitting neurologic disease with extensive plaque-like demyelination. This Cysteine containing MOG 8 - 22 peptide can be use to induced polyclonal anti-MOG 8 - 22 antibody production in rabbits with high specificity, high affinity, and high titer indicating its high purity, as well as suitability for peptide-coated ELISA and Western blot assay. Immunization with MOG 8 - 22 suppresses spontaneous regeneration of dopaminergic neurons injured with MPTP. Multiple Sclerosis: MOG 8 - 22 induced experimental autoimmune encephalomyelitis (EAE) rodent models
| Sequence: | PGYPIRALVGDEQED | |
| Gene: | mog | |
| Delivery: | 3 weeks | |
| C-Terminus: | OH | |
| N-Terminus: | H | |
| Amount: | 1 mg | |
| Counter Ion: | TFA | |
| Protein: | Myelin oligodendrocyte glycoprotein | |
| Species: | rat | |
| Allele: | ||
| Application : | Multiple Sclerosis | |
| Purity : | 95% HPLC-MS |
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€126.80*
Available, delivery time: 3-4 weeks
sterile and endotoxin free
Delivery Format: The product is supplied freeze dried.
Purity: 95% HPLC-MS