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MOG 42 - 54

Myelin oligodendrocyte glycoprotein (MOG) 42-54, a minor component of CNS myelin, is expressed in central nervous system myelin which produces a relapsing-remitting neurological diesease with extensive plague-like demyelination. It is believed to be a target autoantigen in multiple sclerosis. MOG 42-54 peptide is an immunodominant epitope of MOG that induces strong T and B cell responses and Induces experimental autoimmune encephalomyelitis in rodents. A single injection of this peptide produces a relapsing-remitting neurologic disease with extensive plaque-like demyelination. This Cysteine containing MOG 42-54 peptide can be use to induced polyclonal anti-MOG(42-54) antibody production in rabbits with high specificity, high affinity, and high titer indicating its high purity, as well as suitability for peptide-coated ELISA and Western blot assay. Immunization with MOG (42-54) suppresses spontaneous regeneration of dopaminergic neurons injured with MPTP. Multiple Sclerosis: MOG 42-54 induced experimental autoimmune encephalomyelitis (EAE) rodent modelsMyelin oligodendrocyte glycoprotein (MOG) 42-54, a minor component of CNS myelin, is expressed in central nervous system myelin which produces a relapsing-remitting neurological diesease with extensive plague-like demyelination. It is believed to be a target autoantigen in multiple sclerosis. MOG 42-54 peptide is an immunodominant epitope of MOG that induces strong T and B cell responses and Induces experimental autoimmune encephalomyelitis in rodents. A single injection of this peptide produces a relapsing-remitting neurologic disease with extensive plaque-like demyelination. This Cysteine containing MOG 42-54 peptide can be use to induced polyclonal anti-MOG(42-54) antibody production in rabbits with high specificity, high affinity, and high titer indicating its high purity, as well as suitability for peptide-coated ELISA and Western blot assay. Immunization with MOG (42-54) suppresses spontaneous regeneration of dopaminergic neurons injured with MPTP. Multiple Sclerosis: MOG 42-54 induced experimental autoimmune encephalomyelitis (EAE) rodent models

Sequence:SPFSRVVHLYRNG
Gene:mog
Delivery: 3 weeks
C-Terminus:OH
N-Terminus:H
Amount:1 mg
Counter Ion:TFA
Protein:Myelin oligodendrocyte glycoprotein
Species:Mouse, Rat
Allele:
Application :Multiple Sclerosis
Purity :95% HPLC-MS
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€120.75*

Delivery time 2-3 days
sterile and endotoxin free
Delivery Format: The product is supplied freeze dried.
Purity: 95% HPLC-MS
Amount in mg
Product number: EP09871_1