MOG 35 - 51
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Delivery time 3 weeks
sterile and endotoxin free
Delivery Format: The product is supplied freeze dried.
- Order number: EP09861_1
Myelin oligodendrocyte glycoprotein (MOG) 35-51, a minor component of CNS myelin, is expressed in central nervous system myelin which produces a relapsing-remitting neurological diesease with extensive plague-like demyelination. It is believed to be a target autoantigen in multiple sclerosis. MOG 35-51 peptide is an immunodominant epitope of MOG that induces strong T and B cell responses and Induces experimental autoimmune encephalomyelitis in rodents. A single injection of this peptide produces a relapsing-remitting neurologic disease with extensive plaque-like demyelination. This Cysteine containing MOG (35-51) peptide can be use to induced polyclonal anti-MOG(35-51) antibody production in rabbits with high specificity, high affinity, and high titer indicating its high purity, as well as suitability for peptide-coated ELISA and Western blot assay. Immunization with MOG (35-51) suppresses spontaneous regeneration of dopaminergic neurons injured with MPTP.
| Sequence: | MEVGWYRSPFSRVVHLY | |
| Gene: | mog | |
| Delivery: | 3 weeks | |
| C-Terminus: | OH | |
| N-Terminus: | H | |
| Purity: | 95% | |
| Amount: | 1 mg | |
| Counter Ion: | TFA | |
| Protein: | Myelin oligodendrocyte glycoprotein | |
| Species: | Mouse, Rat | |
| Application : | Multiple Sclerosis |
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