MOG 35 - 53
Myelin oligodendrocyte glycoprotein (MOG) 35-53, a minor component of CNS myelin, is expressed in central nervous system myelin which produces a relapsing-remitting neurological diesease with extensive plague-like demyelination. It is believed to be a target autoantigen in multiple sclerosis. MOG 35-53 peptide is an immunodominant epitope of MOG that induces strong T and B cell responses and Induces experimental autoimmune encephalomyelitis in rodents. A single injection of this peptide produces a relapsing-remitting neurologic disease with extensive plaque-like demyelination. This Cysteine containing MOG (35-53) peptide can be use to induced polyclonal anti-MOG(35-53) antibody production in rabbits with high specificity, high affinity, and high titer indicating its high purity, as well as suitability for peptide-coated ELISA and Western blot assay. Immunization with MOG (35-53) suppresses spontaneous regeneration of dopaminergic neurons injured with MPTP.
Sequence: | MEVGWYRSPFSRVVHLYRN | |
Gene: | mog | |
Delivery: | 3 weeks | |
C-Terminus: | OH | |
N-Terminus: | H | |
Amount: | 1 mg | |
Counter Ion: | TFA | |
Protein: | Myelin oligodendrocyte glycoprotein | |
Species: | Mouse, Rat | |
Allele: | ||
Application : | Multiple Sclerosis | |
Purity : | 95% HPLC-MS |
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Data sheets
Safety data sheet poly peptides:For your convenience, we have compiled a selection of publications
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€205.30*
sterile and endotoxin free
Delivery Format: The product is supplied freeze dried.
Purity: 95% HPLC-MS