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HPV 16/18 E7 12-20 (HLA-A*02:01)
( MLDLQPETT )

MLDLQPETT is a linear peptidic epitope (epitope ID41919) studied as part of Protein E7 (UniProt:P03129) from Human papillomavirus type 16 and Protein E7 (UniProt:P06788) from Human papillomavirus type 18. This epitope has been tested in T cell assays, B cell assays and MHC ligand assays.

Sequence:	MLDLQPETT
Gene:	E7
Delivery:	1-3 days
C-Terminus:	OH
N-Terminus:	H
Amount:	1 mg
Counter Ion:	TFA
Protein:	Protein E7
UniProt Id:	P03129
Species:	HPV 16, HPV 18
Allele:	HLA-A*02:01
Application :	Flow Cytometry
Indication :	Infectious disease, Cancer
Purity :	95% HPLC-MS

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€63.50*

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Delivery time 2-3 days
sterile and endotoxin free
Delivery Format: The product is supplied freeze dried.
Purity: 95% HPLC-MS

Amount in mg

1 mg

5 mg

Product number: EP11292_1

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HPV 16 E7 5-13 (HLA-B*07:02) ( KPTLKEYVL )

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HPV 16/18 E7 11-19 (HLA-A*02:01) ( YMLDLQPET )

YMLDLQPET is a linear peptide epitope corresponding to residues 11 through 19 of the E7 oncoprotein from Human papillomavirus type 16 (HPV-16, UniProt: P03129) and HPV-18 (UniProt: P06788). Classified under epitope ID 75074, this sequence is associated with the Alphapapillomavirus 9 and Alphapapillomavirus 7 species groups, respectively. This HLA-A*02:01-restricted epitope has been extensively characterized for its immunological relevance, including its capacity to be recognized by both CD8⁺ T cells and B cells. It has been tested in T cell functional assays, B cell reactivity assays, and MHC class I ligand binding studies, highlighting its value in HPV-specific immune monitoring and vaccine development. The E7 protein itself plays a central role in HPV-driven oncogenesis. It interferes with host immune responses, making E7-derived epitopes such as YMLDLQPET particularly important in the context of cancer immunotherapy research. This peptide is frequently used in experimental settings involving antigen presentation, cytotoxic T lymphocyte responses, and the evaluation of HPV-targeted immunotherapeutic strategies.

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HPV 16/18 E7 11-20 (HLA-A*02:01) ( YMLDLQPETT )

YMLDLQPETT is a linear epitope spanning amino acids 11 to 20 of the E7 oncoproteins from Human papillomavirus type 16 (HPV-16, UniProt: P03129) and type 18 (HPV-18, UniProt: P06788), both high-risk, oncogenic HPV types. The peptide listed under the epitope ID 75075. The peptide is presented by HLA-A*02:01, a common MHC class I allele, and has been extensively validated for its immunogenic potential. It has been extensively tested in T cell assays, B cell assays, and MHC binding assays, highlighting its broad application in HPV-specific immunity studies and vaccine research. The E7 protein plays a pivotal role in HPV-mediated carcinogenesis by disrupting immune recognition pathways. Peptides derived from this region, such as YMLDLQPETT, are of particular interest for T cell-based immunotherapies. This peptide is available from stock and ready for immediate shipping to support your research needs.

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HPV 16/18 E7 12-20 (HLA-A*02:01) ( MLDLQPETT )

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HPV 16/18 E7 49-57 (H-2 Db) ( RAHYNIVTF )

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