Structure of HPV16/18 E7 11-20 (HLA-A*02:01)
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Infectious disease

HPV16/18 E7 11-20 (HLA-A*02:01) YMLDLQPETT

Product number: EP11293_1

€105.00*

Prices excl. VAT plus shipping costs
Available, delivery time: 1-3 days
sterile and endotoxin free
Delivery Format: The product is supplied freeze dried.
Purity: 95% HPLC-MS
Caution: For research use only. Not for use in humans.
Amount in mg
1
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Description

YMLDLQPETT is a linear epitope spanning amino acids 11 to 20 of the E7 oncoproteins from Human papillomavirus type 16 (HPV-16, UniProt: P03129) and type 18 (HPV-18, UniProt: P06788), both high-risk, oncogenic HPV types. The peptide listed under the epitope ID 75075.

The peptide is presented by HLA-A*02:01, a common MHC class I allele, and has been extensively validated for its immunogenic potential. It has been extensively tested in T cell assays, B cell assays, and MHC binding assays, highlighting its broad application in HPV-specific immunity studies and vaccine research.

The E7 protein plays a pivotal role in HPV-mediated carcinogenesis by disrupting immune recognition pathways. Peptides derived from this region, such as YMLDLQPETT, are of particular interest for T cell-based immunotherapies.

This peptide is available from stock and ready for immediate shipping to support your research needs.

TechData

Sequence: YMLDLQPETT
Gene: E7
Delivery: 1-3 days
C-Terminus: OH
N-Terminus: H
Amount: 1 mg
Counterion: TFA
Protein: Protein E7
UniProt Id: P03129
Species: HPV 16, HPV 18
Allele: HLA-A*02:01
Application: Flow Cytometry
Indication: Infectious disease, Cancer
Purity: 95% HPLC-MS