NY-ESO-1 93-101 (HLA-B*07:02) AMPFATPME
€105.00*
Description
The peptide epitope NY-ESO-1 93–101 (AMPFATPME) is derived from the human cancer/testis antigen 1 (NY-ESO-1) with the UniProt-ID P78358. This nonamer peptide (IEDB epitope ID: 2265540) is restricted to HLA-B*07:02 and has been investigated for its role in antigen-specific T cell responses in cancer immunology.
NY-ESO-1 and CTAs
NY-ESO-1 belongs to the family of cancer/testis antigens (CTAs), proteins typically restricted to germ cells of the testis but aberrantly expressed in many tumors, including melanoma, lung, ovarian, and esophageal cancers. Because of this unique expression profile and their strong immunogenicity, CTAs like NY-ESO-1 are widely recognized as prime targets for cancer immunotherapy, immune monitoring, and vaccine development.
NY-ESO-1 epitopes such as AMPFATPME contribute to dissecting CD8⁺ T cell responses and advancing the development of diagnostic assays and adoptive T cell therapies.
T cell epitope cluster
This peptide is part of an immunodominant epitope cluster. Depending on your HLA-restriction of interest, you might also consider:
- NY-ESO-1 86-94 (RLLEFYLAM) – Optimized for HLA-A*02:01
- NY-ESO-1_LAGE-2 91-101 (YLAMPFATPME) – Optimized for HLA-A*24:02
- NY-ESO-1 94-102 (MPFATPMEA) – Optimized for HLA-B*35:01 & HLA-B*51:01
peptides&elephants supplies NY-ESO-1 93–101 with uncompromising quality, enabling reliable, reproducible, and translationally relevant results for immunological research.
TechData
| Sequence: | AMPFATPME |
| Gene: | CTAG1A |
| Delivery: | 1-3 days |
| C-Terminus: | OH |
| N-Terminus: | H |
| Amount: | 1 mg |
| Counterion: | TFA |
| Protein: | Cancer testis antigen, NY-ESO-1 |
| Species: | Human |
| Allele: | HLA-B*07:02 |
| Application: | Flow Cytometry |
| Indication: | Cancer |
| Purity: | 95% HPLC-MS |
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