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Cancer

PRAME/OIP4 Peptide Pool, human

Product number: LB01686

€285.00*

Prices excl. VAT plus shipping costs
Available, delivery time: 1-3 days
sterile and endotoxin free
Delivery Format: The product is supplied freeze dried.
Caution: For research use only. Not for use in humans.
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Description

Pool of 125 overlapping peptides derived from a peptide scan (15mers with 11 aa overlap) through Melanoma antigen preferentially expressed in tumors (PRAME/OIP4) (UniProt ID: P78395) of Homo sapiens (Human).

One unit allows the stimulation of 2,5 x 108 cells.

You can find applications and references in our blog post: Esophagogastric adenocarcinoma: Tumor-associated antigens, immune responses and HLA-I Expression

TechData

Gene: PRAME
Delivery: 1-3 days
Counterion: TFA
Length: 509 amino acids
No. Peptides: 125 peptides
Amount/Aliquote: 15 nmol (approx. 25µg)/peptide for stimulation of 2,5 x 108 cells
Solubility: Dissolve in a minimum amount of pure DMSO (40µl) and dilute with water to the desired concentration. Please pay attention that the final concentration of DMSO must be below 1% (v/v) to avoid toxicity in the biological system.
Protein: Melanoma antigen preferentially expressed in tumors
UniProt Id: P78395
Species: Human
Application: T-cell assays, Immune monitoring, Antigen specific T-cell stimulation, T-cell expansion, Cellular immune response
Indication: Cancer

Documents

Material data sheet Safety data sheet Storage and handling of peptides Probing of membranes with HRP

References

Thelen M, Keller D, Lehmann J, et al.: Immune responses against shared antigens are common in esophago-gastric cancer and can be enhanced using CD40-activated B cells. Journal for ImmunoTherapy of Cancer 2022;10:e005200. doi: 10.1136/jitc-2022-005200
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