Infectious disease
EBV BMLF-1 280-288 (HLA-A*02:01) GLCTLVAML
Product number: EP07604_5
€210.00*
Prices excl. VAT plus shipping
costs
Available, delivery time:
1-3 days
sterile and endotoxin free
Delivery Format: The product is supplied freeze dried.
Purity:
95% HPLC-MS
Caution:
For research use only. Not for use in humans.
Amount in mg
1
Description
EBV peptide GLCTLVAML (HLA-A*0201) for stimulation of T-cells. Single peptide (GLCTLVAML) for stimulation of human EBV BMLF-1(280-288) CD8+ T-cells. The peptide is synthesised as it is presented by the MHC class I HLA-A*0201 allele.
TechData
| Sequence: | GLCTLVAML |
| Gene: | BMLF1 |
| Delivery: | 1-3 days |
| C-Terminus: | OH |
| N-Terminus: | H |
| Amount: | 5 mg |
| Counterion: | TFA |
| Protein: | mRNA export factor ICP27 homolog |
| Species: | Epstein-Barr virus (EBV; Human herpesvirus 4) |
| Allele: | HLA-A*02:01 |
| Application: | T-cell assays, Immune monitoring, Antigen specific T-cell stimulation, T-cell expansion, Cellular immune response |
| Indication: | Infectious disease, Cancer, Neuroscience |
| Purity: | 95% HPLC-MS |
Documents
References
1) Steven, N M et al. “Immediate early and early lytic cycle proteins are frequent targets of the Epstein-Barr virus-induced cytotoxic T cell response.” The Journal of experimental medicine vol. 185,9 (1997): 1605-17. doi:10.1084/jem.185.9.1605
2) van Osch, Thijs L J et al. “Altered Fc glycosylation of anti-HLA alloantibodies in hemato-oncological patients receiving platelet transfusions.” Journal of thrombosis and haemostasis : JTH vol. 20,12 (2022): 3011-3025. doi:10.1111/jth.15898
3) Ning, Jianfang et al. “Functional virus-specific memory T cells survey glioblastoma.” Cancer immunology, immunotherapy : CII vol. 71,8 (2022): 1863-1875. doi:10.1007/s00262-021-03125-w
Further studies that have used the peptide GLCTLVAML:
Mazouz, Sabrina et al. “Expansion of Unique Hepatitis C Virus-Specific Public CD8+ T Cell Clonotypes during Acute Infection and Reinfection.” Journal of immunology (Baltimore, Md. : 1950) vol. 207,4 (2021): 1180-1193. doi:10.4049/jimmunol.2001386
Bajwa, Gagan et al. “Transgenic CD8αβ co-receptor rescues endogenous TCR function in TCR-transgenic virus-specific T cells.” Journal for immunotherapy of cancer vol. 8,2 (2020): e001487. doi:10.1136/jitc-2020-001487
2) van Osch, Thijs L J et al. “Altered Fc glycosylation of anti-HLA alloantibodies in hemato-oncological patients receiving platelet transfusions.” Journal of thrombosis and haemostasis : JTH vol. 20,12 (2022): 3011-3025. doi:10.1111/jth.15898
3) Ning, Jianfang et al. “Functional virus-specific memory T cells survey glioblastoma.” Cancer immunology, immunotherapy : CII vol. 71,8 (2022): 1863-1875. doi:10.1007/s00262-021-03125-w
Further studies that have used the peptide GLCTLVAML:
Mazouz, Sabrina et al. “Expansion of Unique Hepatitis C Virus-Specific Public CD8+ T Cell Clonotypes during Acute Infection and Reinfection.” Journal of immunology (Baltimore, Md. : 1950) vol. 207,4 (2021): 1180-1193. doi:10.4049/jimmunol.2001386
Bajwa, Gagan et al. “Transgenic CD8αβ co-receptor rescues endogenous TCR function in TCR-transgenic virus-specific T cells.” Journal for immunotherapy of cancer vol. 8,2 (2020): e001487. doi:10.1136/jitc-2020-001487