HPV16/18 E7 11-19 (HLA-A*02:01) YMLDLQPET
€105.00*
Description
YMLDLQPET is a linear peptide epitope corresponding to residues 11 through 19 of the E7 oncoprotein from Human papillomavirus type 16 (HPV-16, UniProt: P03129) and HPV-18 (UniProt: P06788). Classified under epitope ID 75074, this sequence is associated with the Alphapapillomavirus 9 and Alphapapillomavirus 7 species groups, respectively.
This HLA-A*02:01-restricted epitope has been extensively characterized for its immunological relevance, including its capacity to be recognized by both CD8⁺ T cells and B cells. It has been tested in T cell functional assays, B cell reactivity assays, and MHC class I ligand binding studies, highlighting its value in HPV-specific immune monitoring and vaccine development.
The E7 protein itself plays a central role in HPV-driven oncogenesis. It interferes with host immune responses, making E7-derived epitopes such as YMLDLQPET particularly important in the context of cancer immunotherapy research.
This peptide is frequently used in experimental settings involving antigen presentation, cytotoxic T lymphocyte responses, and the evaluation of HPV-targeted immunotherapeutic strategies.
TechData
| Sequence: | YMLDLQPET |
| Gene: | E7 |
| Delivery: | 1-3 days |
| C-Terminus: | OH |
| N-Terminus: | H |
| Amount: | 1 mg |
| Counterion: | TFA |
| Protein: | Protein E7 |
| UniProt Id: | P03129 |
| Species: | HPV 16, HPV 18 |
| Allele: | HLA-A*02:01 |
| Application: | Flow Cytometry |
| Indication: | Infectious disease, Cancer |
| Purity: | 95% HPLC-MS |
More HPV E7 Peptides
HPV Peptide Pools
