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Structure of Influenza A HA 116-131 Peptide

Infectious disease

Influenza A HA 116-131 Peptide YDVPDYASLRSLVASS

Product number: EP21288_1

€133.20*

Prices excl. VAT plus shipping costs

Available, delivery time: 1-3 days

sterile and endotoxin free

Delivery Format: The product is supplied freeze dried.

Purity: 95% HPLC-MS

Caution: For research use only. Not for use in humans.

Amount in mg

1

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Description

The Influenza A HA 116–131 Peptide (epitope ID 73603) is an extended 16-mer CD4+ T-cell epitope derived from the HA1 subunit of Influenza A Hemagglutinin (H3N2). Binding for this MHC Class II ligand has been experimentally validated for HLA-DRB1*01:01, HLA-DRB1*04:01, and HLA-DRB1*07:01.

In canonical UniProt entries such as P03437 for A/Aichi/2/1968 or related H3N2 strains like A/Beijing/32/1992, the sequence YDVPDYASLRSLVASS corresponds to amino acids 116–131 of the precursor protein, which represents residues 98–113 of the mature HA1 chain following signal peptide cleavage.

Encompassing the well-known core motif YDVPDYASL, this specific 16-amino-acid sequence has been evaluated in specialized immunological studies (e.g., Gelder et al., 1998) to investigate MHC Class II binding capacity and CD4+ T-cell reactivity. It serves as a targeted peptide for Influenza-specific T-cell assays and epitope characterization.

TechData

Sequence:	YDVPDYASLRSLVASS
Gene:	HA
Delivery:	1-3 days
C-Terminus:	OH
N-Terminus:	H
Amount:	1 mg
Counterion:	TFA
Protein:	Hemagglutinin
UniProt Id:	P03437
IEDB Id:	73603
Species:	Influenza A virus
Allele:	HLA-DRB101:01, HLA-DRB104:01, HLA-DRB1*07:01
Application:	Antigen specific T-cell stimulation, T-cell assays, T-cell expansion
Indication:	Infectious disease
Purity:	95% HPLC-MS

Documents

Storage and handling of peptides

Probing of membranes with HRP

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