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Peptide Blog by peptides & elephants

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Peptide Alarm Therapy: A Novel Approach to overcome Immunosuppressive Tumor Microenvironments
December 11, 2024   Dr. Lilian Schoefer
Research updates   cancer, t-cell, cytomegalovirus
An immunosuppressive tumor microenvironment is a major challenge for existing immunotherapies. A novel form of immunotherapy, known as peptide alarm therapy, has shown promise in activating the immune system within tumors by injecting viral peptides.
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Infographic of Peptide Alarm Therapy: Viral peptides label tumor cells for destruction by pre-existing memory T-cells.

Neoantigene-Specific T-Cells in TIL Therapy
July 29, 2024   Dr. Lilian Schoefer
Research updates   cancer, t-cell
The newly approved Lifileucel stimulates tumor-infiltrating lymphocytes (TILs) unspecifically. Researchers are now investigating the degree to which neoantigens contribute to tumor regression under TIL therapy.
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Drawing of a T cell and a cancer cell with MHC-I and CD8+

Epstein-Barr virus: Mechanisms of cancer development decoded
October 4, 2023   Dr. Lilian Schoefer
Research updates   cancer
Over 90 percent of adults worldwide are infected with the Epstein-Barr virus (EBV). The virus belongs to the herpes viruses and stays in the body for a lifetime.
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Two pie charts comparing LMP-1 GGDPHLPTL peptide variants in Epstein-Barr virus asymptomatic reactivation for EBV HL and EBV nHL with labeled segments and a note on host conditions below
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