beta-Amyloid (11-40) EVHHQKLVFFAEDVGSNKGAIIGLMVGGVV
€266.20*
Description
Post-mortem Alzheimer’s diseased brain specimens reveals significant levels of Aß (11-40/42) within insoluble amyloid pools. The ß-secretase enzyme or ß-amyloid precursor protein-cleaving enzyme (BACE) generates the N terminus of Aß, ultimately leading to the production of full-length Aß (1-40/42) or truncated Aß (11-40/42). The abundance of Aß (11-40/42) produced by BACE suggests that their roles in AD pathogenesis may be important.
TechData
| Sequence: | EVHHQKLVFFAEDVGSNKGAIIGLMVGGVV |
| Gene: | APP |
| Delivery: | 1-3 days |
| C-Terminus: | OH |
| N-Terminus: | H |
| Amount: | 1 mg |
| Counterion: | TFA |
| Protein: | Amyloid-beta precursor protein |
| UniProt Id: | P05067 |
| IEDB Id: | 157223 |
| Species: | Human |
| Application: | ELISPOT, Flow Cytometry, Western Blotting |
| Indication: | Neuroscience |
| Purity: | 95% HPLC-MS |
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