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On January 31, 2024, 14 students from Oranienburg's Louise-Henriette-Gymnasium visited peptides&elephants in Hennigsdorf near Berlin. Spearheading the excursion was chemistry and biology teacher, Dr. Enrico Brandenburg, as part of the career orientation project week.
For patients with acute myeloid leukemia, allogeneic hematopoietic stem cell transplantation is an important and sometimes life-saving therapy. However, the relapse rates are very high at 40 to 70 percent. An infection with cytomegalovirus (CMV) poses a further threat to transplant recipients. But if the virus reactivates after transplantation, it may also protect against a leukemia relapse. To better understand this controversial observation, scientists led by Xiao-Hua Luo and Per Ljungman from the Karolinska Institutet in Stockholm, Sweden, examined the peripheral blood mononuclear cells of leukemia patients after stem cell transplantation. Using FACS analysis and peptide pools from peptides&elephants, they tested whether reactivation of the cytomegalovirus influences T cell immunity against Wilms tumor 1 - and thus against leukemia cells. Peptide pools represent a complete protein by mapping its primary amino acid sequence into individual 15mer peptides, each overlapping by 11 amino acids. The scientists published their results in Frontiers in Immunology.
Over 90 percent of adults worldwide are infected with the Epstein-Barr virus (EBV). The virus belongs to the herpes viruses and stays in the body for a lifetime. It causes glandular fever, but it can also develop into Hodgkin's or non-Hodgkin's lymphoma after several years of reactivations. The circumstances under which this happens have not yet been clarified.

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The 2023 annual meeting of the American Association of Immunologists (AAI) will take place at the Walter E. Washington Convention Center in Washington D.C. from May 11th to May 15th. Peptides & Elephants is excited to participate ...

Personalized Cancer Vaccines

The federal research grant approved - ProFIT Brandenburg Program and ProFIT Brandenburg Program and the European Union via its European Regional Development Fund (ERDF) ...