Each individual library peptide is well characterized, cleaved and shipped lyophilized in a single vial or composed in microtiter plates.
Post-translational modifications, can be defined incorporated. Phosphorylation, Acetylation, Oxidation, Amidation, Methylation, Palmitoylation, Sulfation, full conversions of Arginine to Citrulline, Glutamic acid to Pyro-glutamine and Palmitoylation of cysteine (S-palmitoylation), serine and threonine are synthetically representable.
Cyclisation to arrange defined structures, non-natural building blocks like D-Amino acids and organic molecules can be added.
p&e′s peptide libraries are ideal to execute Structure-Activity-Relationship (SAR Analyses), T-Cell Stimulation, Neoantigen Characterization, Proteome Analyses and Vaccine development.
PEPTIDE LIBRARIES
Type | Application | Quality | SCALE |
---|---|---|---|
RESEARCH
Inquiry-Link |
Immunological research T-cell epitope discovery, Antigen target identification, Pathogen-spanning, T-cell epitope discovery, Neo-epitope prioritization, Target identification, Biological screening Drug discovery SAR Analysis (structure/activity relationship) |
Sequence Save Synthesis - via Capping Purification: precipitate and extended washing QA: Randomized 5% ESI-MS Free of endotoxins and sterile |
2µmol app. 1-2mg |
TRIAL
Inquiry-Link |
Immune monitoring Immunotherapy development Drug discovery SAR Analysis (structure/activity relationship) |
Sequence Save Synthesis - via Capping Purification: precipitate and extended washing QA: 100% ESI-MS, average purity 70% Free of endotoxins and sterile |
2µmol app. 1-2mg |
CLINICAL GRADE
Inquiry-Link |
Adoptive Therapy Personalized Neoantigens Personalized Immune Therapies | GLP Purification: HPLC QA: 100% HPLC-MS, >90% pure TSE/BSE certificate Free of endotoxins and sterile FDA conform QA on request |
On demand |
peptides & elephants customized libraries are powerful tools for
- Antigen-specific stimulation in T-cell assays
- Immune monitoring
- T-cell epitope identification
- T-cell epitope mapping
- Development of cellular therapy and immunotherapy approaches
- Vaccine development
- Biological screening
- Protein-protein interaction analyses
Further specifications
for p&e libraries
Minimum Order: 24 peptides
Peptide Length: 6-15 aa (all peptides in one order must have the same length)
Mass spectra and HPLC-analysis of purified peptides are included in delivery
Peptides are N-Terminal free amine and C-Terminal amide and without modifications
Peptides are delivered lyophilized Counter ion: TFA
Possible modifications on request are available at extra charge.
We can offer the following modifications:
- Phosphorylated Ser, Thr, Tyr
- D-Amino Acids
- N-terminal acetylation
- N-terminal fluorescent label
- N-terminal biotin
- C-terminal acid
- Non natural amino acids