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Structure of NY-ESO-1 86-94 (HLA-A*02:01)
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Cancer

NY-ESO-1 86-94 (HLA-A*02:01) RLLEFYLAM

€105.00*

Prices excl. VAT plus shipping costs
Available, delivery time: 1-3 days
sterile and endotoxin free
Delivery Format: The product is supplied freeze dried.
Purity: 95% HPLC-MS
Caution: For research use only. Not for use in humans.
Amount in mg
1
Add to Cart
Product number: EP11498_1

Description

NY-ESO-1 86–94 (RLLEFYLAM) is a well-characterized linear peptide epitope derived from the human cancer/testis antigen 1 (NY-ESO-1, UniProt: P78358). Restricted to HLA-A*02:01, this nonamer peptide has been extensively studied for its immunogenic potential in cancer immunology.

According to the Immune Epitope Database (IEDB epitope ID: 1075626), RLLEFYLAM has at least been:

  • Reported in 6 peer-reviewed publications
  • Tested in 7 T cell assays, demonstrating strong CD8⁺ T cell reactivity
  • Assessed in 1 B cell assay and 2 MHC ligand assays

Background on NY-ESO-1 and CTAs

NY-ESO-1 is one of the most immunogenic cancer/testis antigens (CTAs). CTAs are normally expressed only in germ cells of the testis but become aberrantly re-expressed in many cancers, including melanoma, lung, ovarian, and esophageal tumors. Because the testis is an immune-privileged site, the immune system does not develop tolerance to these antigens—making them highly attractive targets for cancer immunotherapy and immune monitoring.

These characteristics have positioned NY-ESO-1, and epitopes like RLLEFYLAM, at the center of research into cancer vaccines, adoptive T cell therapies, and diagnostic assays.

T cell epitope cluster

This peptide is part of an immunodominant cluster. Depending on your HLA-restriction of interest, you might also consider:

peptides&elephants provides NY-ESO-1 86–94 with the highest quality standards, ensuring reliable results in immunological research and translational applications.

TechData

Sequence: RLLEFYLAM
Gene: CTAG1A
Delivery: 1-3 days
C-Terminus: OH
N-Terminus: H
Amount: 1 mg
Counterion: TFA
Protein: Cancer testis antigen, NY-ESO-1
Species: Human
Allele: HLA-A*02:01
Application: Flow Cytometry
Indication: Cancer
Purity: 95% HPLC-MS

Documents

Material data sheet Safety data sheet Storage and handling of peptides Probing of membranes with HRP
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