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EBV EBNA2 280-290 (DRB1*01:01)
( TVFYNIPPMPL )



The peptide EBV EBNA2 280–290 (TVFYNIPPMPL) from peptides&elephants is a synthetic antigenic epitope derived from Epstein–Barr nuclear antigen 2 (EBNA2) of Epstein–Barr virus (Human herpesvirus 4). EBNA2 is a central transcriptional regulator expressed during early stages of EBV infection and plays a crucial role in the establishment of viral latency and the reprogramming of infected B cells.

For a deeper understanding of the biological role of EBNA2 in early EBV infection and viral transcriptional control, explore the EBV Peptide Insights section by peptides&elephants.
 
EBV EBNA2 280–290 corresponds to a linear T-cell epitope (IEDB ID 67007) located within the EBNA2 protein (UniProt ID: P12978). It has been experimentally studied for immune reactivity and evaluated in multiple functional T-cell assays. The epitope is presented in the context of HLA-DRB1*01:01, enabling recognition by CD4⁺ T cells.
 
Experimental studies have demonstrated positive immune responses in several assay formats, including interferon-γ (IFNγ) release assays, T-cell proliferation assays, and cytotoxicity assays. These findings indicate that the peptide can effectively stimulate EBNA2-specific T-cell responses and is therefore suitable for applications in cellular immunology and EBV research.
 
Because EBNA2 is a key driver of early transcriptional reprogramming in EBV-infected cells, peptides derived from this protein are valuable tools for studying virus-host interactions, T-cell immunity to EBV, and immune recognition of latency-associated antigens.
 
Applications
  • Stimulation of EBV-specific T cells
  • ELISpot and FluoroSpot assays
  • Intracellular cytokine staining (ICS)
  • T-cell proliferation assays
  • Cytotoxicity assays
  • Epitope validation and immune monitoring in EBV research
Sequence:TVFYNIPPMPL
Gene:EBNA2
Delivery:1-3 days
C-Terminus:OH
N-Terminus:H
Amount:1 mg
Counter Ion:TFA
Protein:Epstein-Barr nuclear antigen 2
Species:Epstein-Barr virus (EBV; Human herpesvirus 4)
Allele:
Application :Cellular immune response, Immune monitoring, T-cell assays, Immunohistochemistry
Indication :Infectious disease, Cancer, Neuroscience
Purity :95% HPLC-MS
Special references for this product will come soon.
For your convenience, we have compiled a selection of publications
where our peptide products have been employed:
Publications >

€109.20*

Prices excl. VAT plus shipping costs

Delivery time 2-3 days
sterile and endotoxin free
Delivery Format: The product is supplied freeze dried.
Purity: 95% HPLC-MS
Amount in mg
Product number: EP20308_1

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