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Structure of Influenza A M1 58-66 (HLA-A*02:01)
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Infectious disease

Influenza A M1 58-66 (HLA-A*02:01) GILGFVFTL

Product number: EP07854_5

€210.00*

Prices excl. VAT plus shipping costs
Available, delivery time: 1-3 days
sterile and endotoxin free
Delivery Format: The product is supplied freeze dried.
Purity: 95% HPLC-MS
Caution: For research use only. Not for use in humans.
Amount in mg
1
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Description

GILGFVFTL is a HLA-A2-restricted epitope from influenza matrix M1 protein.

TechData

Sequence: GILGFVFTL
Gene: M
Delivery: 1-3 days
C-Terminus: OH
N-Terminus: H
Amount: 5 mg
Counterion: TFA
Protein: Matrix protein 1
UniProt Id: P03485
IEDB Id: https://www.iedb.org/epitope/20354
Species: Influenza A virus
Allele: HLA-A*02:01, HLA-A2, HLA-A*02:06, HLA-A*02:02, HLA-A*02:03, HLA-C*08:01, HLA-A*68:02, HLA-E*01:03, SLA-3*02:02
Application: T-cell assays, Immune monitoring, Antigen specific T-cell stimulation, T-cell expansion, Cellular immune response
Indication: Infectious disease
Purity: 95% HPLC-MS

Documents

Material data sheet Safety data sheet Storage and handling of peptides Probing of membranes with HRP

References

Lanfermeijer, Josien et al. “Modified influenza M1 58-66 peptide vaccination induces non-relevant T-cells and may enhance pathology after challenge.” NPJ vaccines vol. 8,1 116. 12 Aug. 2023, doi:10.1038/s41541-023-00705-y

Dolton, Garry et al. “More tricks with tetramers: a practical guide to staining T cells with peptide-MHC multimers.” Immunology vol. 146,1 (2015): 11-22. doi:10.1111/imm.12499

Kubota, Ryuji et al. "An Altered Peptide Ligand Antagonizes Antigen-Specific T Cells of Patients with Human T Lymphotropic Virus Type I-Associated Neurological Disease". J Immunol 164,10 (2000): 5192–5198. https://doi.org/10.4049/jimmunol.164.10.5192

Di Mario, Giuseppina et al. “Protective immunity against influenza in HLA-A2 transgenic mice by modified vaccinia virus Ankara vectored vaccines containing internal influenza proteins.” Pathogens and global health vol. 111,2 (2017): 76-82. doi:10.1080/20477724.2016.1275465

Boon, A C M et al. “The magnitude and specificity of influenza A virus-specific cytotoxic T-lymphocyte responses in humans is related to HLA-A and -B phenotype.” Journal of virology vol. 76,2 (2002): 582-90. doi:10.1128/jvi.76.2.582-590.2002
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